Chronic Fatigue Syndrome (also known as M.E) is an illness characterized by the symptom of chronic and severe fatigue, in the absence of an alternative medical condition. It has been the subject of intense media debate over recent years. Such interest has been partially due to the polarization of professional and scientific opinion concerning the topic – what is it, and what causes it? Chonic Fatigue and its syndromes presents an objective and comprehensive review of the problem of chronic fatigue, mixing medical, psychological, social, and historical perspectives. It begins by considering the nature of fatigue, and its physical and psychological origins. The book then introduces the subject of CFS, tracing its historical origins, before considering the epidemiology, and the various aetiological theories for modern forms of the condition – viral, immunological, psychologica, psychiatric, and neurological. The book concludes with a clinical section that gives a step by step guide to the assessment and treatment of CFS. Throughout, the authors argue that chronic fatigue and its various syndromes cannot easily be pigeonholed into either physical or psychological categories, and that the ambiguous nature of the illness actually provides us with a valuable chance to explore contemporary attitutes to sickness and health, one not offered by better defined or classified disorders.